Other Antibacterial Agents
- Antiseptics and Disinfectants
- Overview of Antiseptics and Disinfectants
- Acids and Alkalies
- Alcohols
- Biguanides
- Oxidizing Agents
- Metals as Antiseptics and Disinfectants
- Phenols and Related Compounds
- Reducing Agents
- Surface-active Compounds
- Other Antibacterial Agents
- Vapor-phase Disinfectants
The antibacterial activity of dyes was first reported in 1913. Interestingly, the discovery of sulfonamides as chemotherapeutic agents ensued from the antibacterial activity observed in the dye prontosil.
Azo dyes (eg, scarlet red and phenazopyridine HCl) are most active in an acidic medium and are effective against gram-negative organisms. Scarlet red is often used as a 5% ointment on sores, ulcers, and wounds. Pyridium is often incorporated as an analgesic with sulfonamides to treat urinary tract infections.
Acridine dyes (eg, acriflavine, proflavine, aminacrine) are more active against gram-positive bacteria. Their activity is enhanced in alkaline medium and antagonized by hypochlorites. Impregnated bandages and gauze and acriflavine jelly have been used extensively for treatment of burns.
- Antiseptics and Disinfectants
- Overview of Antiseptics and Disinfectants
- Acids and Alkalies
- Alcohols
- Biguanides
- Oxidizing Agents
- Metals as Antiseptics and Disinfectants
- Phenols and Related Compounds
- Reducing Agents
- Surface-active Compounds
- Other Antibacterial Agents
- Vapor-phase Disinfectants
Also of Interest
Test your knowledge
Dogs and cats with left-side congestive heart failure (CHF) can develop respiratory distress due to pulmonary edema. Which of the following intravenous diuretics is the most appropriate treatment for life-threatening pulmonary edema caused by CHF?