Congenital and Inherited Disorders of the Urinary System of Cats

Kidney malformations, called dysplasias, occur when a cat’s kidneys do not develop properly before birth. When the kidneys are unusually small, the condition is called hypoplasia. These abnormalities occur only occasionally in cats. Signs typically develop when cats are between 6 months and 2 years of age, and may include vomiting, decreased appetite, and increased thirst or urination. There is no effective treatment. Care for affected cats consists of managing the problems associated with the kidney failure that results from these conditions.

Rarely, one or both kidneys fail to develop. This condition is always accompanied by a lack of the tube that connects the kidney to the bladder (the ureter). The reproductive organs may also be underdeveloped. A cat in which both kidneys have failed to develop will die shortly after birth. However, a cat with one functioning kidney can live a full and healthy life. In this case, the condition is usually discovered by accident.

Polycystic kidneys have multiple cysts (enclosed, fluid-filled sacs) inside the functional part of the organ. The kidneys may be greatly enlarged, which a veterinarian may be able to feel during a physical examination. Problems caused by this condition can range from none at all to progressive kidney failure. This condition may be inherited in Persian cats and domestic long-haired cats. Your veterinarian can diagnose polycystic kidneys by examining your pet, taking x-rays, performing ultrasonography, or performing exploratory abdominal surgery.

These usually occur as a single cyst. They generally do not interfere with normal kidney function. It is unclear what causes them, and they are usually identified by accident.

Other congenital problems include kidneys that are not positioned correctly, kidneys that are fused together, and nephroblastoma, a cancer that develops in the kidneys of young animals as a result of abnormal kidney tissue growth in the womb.

An ectopic ureter is one that opens somewhere other than into the bladder. Ectopic ureters could empty urine into the urethra (the tube used for urination), or in females, the uterus or vagina. This defect can occur in cats, but it is much more common in dogs ( Congenital and Inherited Disorders of the Urinary System in Dogs : Ectopic Ureter).

Other abnormalities of the ureter include failure to develop, the presence of more than the usual 2 ureters, and enlargement of the end of the ureter that connects to the bladder, a condition that can usually be successfully treated by surgery.

The urachus is a cord of fibrous tissue that normally extends from the bladder to the navel. Before birth, the urachus is a tube that connects the bladder to the umbilical cord so that wastes can be removed. After birth, it normally closes and becomes a solid cord. In some animals, however, the urachus does not close properly after birth. Depending on which portion of the urachus remains open, these abnormalities are called a patent urachus or an umbilical urachal sinus. Other problems include urachal diverticula (small sac-like structures attached to the urachus) and urachal cysts. Signs include an inability to control urination, urine scalding (due to the fact that urine is acidic) of the skin near the navel, and urinary tract infections. Your veterinarian can diagnose these problems using x‑rays taken after a special dye is given intravenously. Treatment usually includes surgery and, sometimes, antibiotics.

Other inherited or congenital bladder conditions in cats include the presence of more than one bladder, an abnormally developed or underdeveloped bladder, failure of the bladder to develop, and a bladder that is turned inside-out. Usually these problems occur along with other abnormalities of the urinary tract. Your veterinarian can diagnose these problems based on physical examination, observation of your pet while it urinates, and contrast x‑rays. Treatment varies depending on the type of problem.