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Veterinary Manual

Find information on animal health topics, written for the veterinary professional.

Disorders of Magnesium Metabolism in Cats

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Disorders of Magnesium Metabolism in Cats

By George M. Barrington, DVM, PhD, DACVIM, Professor, College of Veterinary Medicine, Washington State University ; Jean A. Hall, DVM, PhD, DACVIM, Professor, Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University ; Sharon J. Spier, DVM, PhD, DACVIM, Professor, Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California ; Ivan W. Caple, BVSc, PhD, MACVSc, MRCVS, Dean, Faculty of Veterinary Sciences, Veterinary Clinical Centre, University of Melbourne ; David L. Evans, BVSc, PhD, Associate Professor, Faculty of Veterinary Science, University of Sydney ; Don A. Franco, DVM, MPH, DACVPM, Retired President, Center for Biosecurity Food Safety and Public Health ; Katharine F. Lunn, BVMS, MS, PhD, MRCVS, DACVIM, Associate Professor, Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University ; Donald C. Sawyer, DVM, PhD, Professor Emeritus, Michigan State University

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Most disorders of magnesium metabolism are due to problems associated with absorption of the mineral from the digestive tract. The anatomical differences between species are associated with the importance of disorders of magnesium occurring in a particular species. Disorders of magnesium metabolism are less common in cats than in cattle and sheep. Too much magnesium in the blood (hypermagnesemia) is rare but has been reported in cats with kidney failure that were receiving intravenous fluids. Cardiac arrest can occur with very high blood magnesium levels.

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The acronym SLUD stands for salivation, lacrimation, urination, and defecation, which are the clinical signs associated with muscarinic cholinergic overstimulation caused by certain toxins. Signs of SLUD are most consistent with exposure to which of the following classes of chemicals?